Polynucleotide Skin Boosters

Polynucleotide skin boosters are advanced injectable treatments made from purified DNA fragments that stimulate your skin's natural repair. They activate fibroblasts, the cells that produce new collagen and elastin, rebuilding skin structure and hydration over time rather than adding volume. Highly biocompatible and well researched, they are suitable for all skin types.

You may see them described as regenerative skin treatment, DNA skin boosters or simply polynucleotide injections; the principle is the same. Unlike fillers, which add structure, or hydrating injectables, which add moisture, polynucleotides work at a cellular level to encourage the skin to repair itself, which is why the results build gradually and last.

Both are injectable skin boosters; they work differently. Polynucleotides are regenerative: they stimulate fibroblasts to repair skin at a cellular level, which is why they excel on fragile, stressed and under-eye skin. Profhilo is hyaluronic acid based: deep hydration, elasticity and glow. Many patients ultimately use both in sequence; the consultation decides on your skin, not the trend. And for concerns polynucleotides don't solve, structural volume for instance, fillers are the honest recommendation.

Polynucleotide treatment at Apex Medical is led by Mr Dominic Yue, Consultant Plastic Surgeon, using clinically proven formulations only, administered with precision techniques in a CQC-registered hospital setting. The focus is enhancing skin quality rather than altering features: by stimulating your skin's own repair processes, polynucleotides improve firmness, texture and tone without adding volume. For many patients, treatment forms part of a wider regenerative protocol, which may include Profhilo, microneedling or LED therapy for comprehensive rejuvenation.

Skin assessment, goals, and a personalised plan.

Around 30 minutes, by fine needle or cannula; well tolerated even in the delicate eye area.

Mild swelling or small bumps at injection sites, especially under the eyes, settle within 24 to 48 hours.

First improvements in tone and hydration from sessions one to two; full benefits after two to three. Initial course of three sessions, three to four weeks apart.

A session every six months keeps skin at its best.

Mild swelling or small bumps at the injection sites, especially under the eyes, are normal and settle within 24 to 48 hours. Most patients go straight back to their day; avoid strenuous exercise, alcohol and heat treatments for the first 24 to 48 hours.

Results arrive gradually, and that is the point. Regeneration takes weeks: first improvements in tone and hydration show from sessions one to two, with the full benefit after two to three as collagen and elastin production rises. Keeping to your course schedule matters more here than with any other injectable, so sessions are booked three to four weeks apart and reviewed as you go. At review, your consultant may also discuss combining polynucleotides with Profhilo, microneedling or LED therapy where it would genuinely add to the result.

Apex Medical is based at Berkshire Grove Hospital, Grove House, Waltham Road, White Waltham, Maidenhead SL6 3TN, with clinics also at the Parkside Suite. Patients travel to us from Maidenhead, Windsor, Reading, Bracknell and Slough, and from across Berkshire, Surrey, Oxfordshire and London, for consultant-led care in a regulated private hospital without long waiting times. On-site parking is available.

Opening hours: Monday to Friday, 9:00am to 5:30pm · Saturday by appointment only · Sunday closed
Or call 020 3871 5898

Common questions about polynucleotides at Apex Medical